Hydroxyapatite/Collagen Bone-Like Nanocomposite

Hydroxyapatite/collagen bone-like nanocomposite.

Our group has succeeded to synthesize material with bone-like nanostructure and bone-like inorganic and organic composition via self-organization mechanism between them using simultaneous titration method under controlled pH and temperature. The hydroxyapatite/collagen (HAp/Col) bone-like nanocomposite completely incorporated into bone remodeling process to be substituted by new bone. Cells cul...

Synthesis of Hydroxyapatite/Collagen Bone-Like Nanocomposite and Its Biological Reactions

Bone-Shaped Nanomaterials for Nanocomposite Applications

A novel template synthesis of bone-shaped (dumbbell-shaped, dogbone-shaped) nanomaterials is demonstrated. Porous anodic alumina (PAA) templates with uniform nanochannels were fabricated using a four-step anodization process and used to form bone-shaped carbon nanostructures with stem and end diameters and lengths of 40 nm, 70 nm, and 5 μm, respectively. These nanomaterials, which we refer to a...

Gelatin/hydroxyapatite nanocomposite scaffolds for bone repair

The use of bioscaffolds for tissue repair is widely accepted. They can provide structural stability and a 3D system on which cells can grow new tissue. Natural bone is composed of organic (mainly collagen) and mineral biomaterials (predominantly carbonate hydroxyapatite, HA). In recent years, developments in 3D porous-scaffold manufacturing have increased hopes of successful fabrication of stru...

Advanced Nanocomposite Scaffold for Bone Regeneration

Introduction Each year in the United States approximately 500,000 procedures that involve the use of bone substitutes are performed. To address the limitations of materials currently used in orthopaedic tissue engineering, we have developed novel nanocomposite materials that consist of a citric acid-based elastomer, poly(1,8 octanediol citrate) (POC) and bioceramic nanoparticles, βtricalcium ph...